|Other Names||Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2, D-fructose-6-phosphate amidotransferase 2, Glutamine:fructose-6-phosphate amidotransferase 2, GFAT 2, GFAT2, Hexosephosphate aminotransferase 2, GFPT2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9282c was selected from the Center region of human GFPT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.|
|Tissue Location||Highest levels of expression in heart, placenta, and spinal cord|
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Provided below are standard protocols that you may find useful for product applications.
GFPT2 controls the flux of glucose into the hexosamine pathway. This protein most likely involved in regulating the availability of precursors for N-and O-linked glycosylation of proteins.
Edwards,T.L., et.al., Ann. Hum. Genet. 74 (2), 97-109 (2010)Prasad,P., et.al., BMC Med. Genet. 11, 52 (2010)Srinivasan,V., et.al., Clin. Biochem. 40 (13-14), 952-957 (2007)
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