|Other Names||Arginine and glutamate-rich protein 1, ARGLU1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9290a was selected from the N-term region of human ARGLU1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for the estrogen-dependent expression of ESR1 target genes. Can act in cooperation with MED1.|
|Cellular Location||Nucleus. Note=Recruited, in an estrogen-dependent manner, to ESR1 target gene promoters. Colocalizes with MED1|
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Provided below are standard protocols that you may find useful for product applications.
ARGLU1 belongs to the UPF0430 family. There are two named isoforms.
Olsen,J.V., et.al, Cell 127 (3), 635-648 (2006)Beausoleil,S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)Beausoleil,S.A., et.al, Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
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