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FBXO4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UKT5
Clone Names 91009085
Peptide ID 91009085
Additional Information
Gene ID 26272
Other Names F-box only protein 4, FBXO4, FBX4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9295c was selected from the Center region of human FBXO4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO4
Synonyms FBX4
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.


Zeng,Z.,, Dev. Cell 18 (2), 214-225 (2010)Barbash,O.,, Cancer Cell 14 (1), 68-78 (2008)Sugiyama,N.,, Mol. Cell Proteomics 6 (6), 1103-1109 (2007)

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$ 80.00
Cat# BP9295c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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