|Other Names||Alpha-(1, 3)-fucosyltransferase 5, Fucosyltransferase 5, Fucosyltransferase V, Fuc-TV, FucT-V, Galactoside 3-L-fucosyltransferase, FUT5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9296c was selected from the Center region of human FUT5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi|
|Tissue Location||Liver, colon and testis and trace amounts in T-cells and brain|
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Provided below are standard protocols that you may find useful for product applications.
FUT5 may catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.
Norden,R., et.al, Glycobiology 19 (7), 776-788 (2009)Chiu,P.C., et.al, J. Cell. Sci. 120 (PT 1), 33-44 (2007)Inaba,Y., et.al, Int. J. Cancer 107 (6), 949-957 (2003)
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