|Other Names||Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6, Slc17a6, Dnpi, Vglut2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9300b was selected from the C-term region of human MOUSE VGLU2 Andibody (C-term). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Expressed in brain. Expressed in hippocampal neurons (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
MOUSE VGLU2 mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. This protein may also mediate the transport of inorganic phosphate.
Birgner,C., et.al, Proc. Natl. Acad. Sci. U.S.A. 107 (1), 389-394 (2010)Renier,N., et.al, PLoS Biol. 8 (3), E1000325 (2010)Rose,M.F., et.al, Proc. Natl. Acad. Sci. U.S.A. 106 (52), 22462-22467 (2009)
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