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KLHL7 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IXQ5
Clone Names 91109297
Peptide ID 91109297
Additional Information
Gene ID 55975
Other Names Kelch-like protein 7, KLHL7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9307c was selected from the Center region of human KLHL7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL7
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
Cellular Location Nucleus.
Tissue Location Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis
Research Areas
Citations (0)

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Background

KLHL7 encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation.

References

Friedman,J.S., et.al., Am. J. Hum. Genet. 84 (6), 792-800 (2009)Bredholt,G., et.al, Scand. J. Immunol. 64 (3), 325-335 (2006)

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$ 80.00
Cat# BP9307c
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