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KLHL7 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IXQ5
Clone Names 91109297
Additional Information
Gene ID 55975
Other Names Kelch-like protein 7, KLHL7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9307c was selected from the Center region of human KLHL7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL7
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
Cellular Location Nucleus. Cytoplasm. Note=Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm
Tissue Location Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.
Research Areas
Citations (0)
citation

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Background

KLHL7 encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation.

References

Friedman,J.S., et.al., Am. J. Hum. Genet. 84 (6), 792-800 (2009)Bredholt,G., et.al, Scand. J. Immunol. 64 (3), 325-335 (2006)

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$ 277.78
Cat# BP9307c
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