|Other Names||Prepronociceptin, Neuropeptide 1, Nociceptin, Orphanin FQ, PPNOC, Neuropeptide 2, PNOC, OFQ|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.|
|Tissue Location||Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation|
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PNOC is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. This protein may be involved in neuronal differentiation and development
Kuzmin,A., et.al., Brain Res. 1305 SUPPL, S80-S85 (2009)Rocha,L., et.al., Neurobiol. Dis. 35 (3), 466-473 (2009)de Krom,M., et.al., Biol. Psychiatry 65 (7), 625-630 (2009)
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