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EYA4 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95677
Peptide ID 91009034
Additional Information
Gene ID 2070
Other Names Eyes absent homolog 4, EYA4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EYA4
Function Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Highly expressed in heart and skeletal muscle.
Research Areas
Citations (0)

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EYA4 encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti.


Miller,S.J. Oncogene 29 (3), 368-379 (2010)Li,H. J. Exp. Clin. Cancer Res. 28, 145 (2009)Melzer,D. PLoS Genet. 4 (5), E1000072 (2008)

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$ 80.00
Cat# BP9330b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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