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HAAO Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P46952
Peptide ID 91013093
Additional Information
Gene ID 23498
Other Names 3-hydroxyanthranilate 3, 4-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}, 113116 {ECO:0000255|HAMAP-Rule:MF_03019}, 3-hydroxyanthranilate oxygenase {ECO:0000255|HAMAP-Rule:MF_03019}, 3-HAO {ECO:0000255|HAMAP-Rule:MF_03019}, 3-hydroxyanthranilic acid dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}, HAD {ECO:0000255|HAMAP-Rule:MF_03019}, HAAO {ECO:0000255|HAMAP-Rule:MF_03019}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HAAO {ECO:0000255|HAMAP-Rule:MF_03019}
Function Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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HAAO is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.


Huang,Y.W. Gynecol. Oncol. 117 (2), 239-247 (2010)Huang,Y.W. Oncol. Rep. 22 (4), 853-861 (2009)Trynka,G. Gut 58 (8), 1078-1083 (2009)

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$ 80.00
Cat# BP9349a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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