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TREF1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96PN7
Additional Information
Gene ID 55809
Other Names Transcriptional-regulating factor 1, Breast cancer anti-estrogen resistance 2, Transcriptional-regulating protein 132, Zinc finger protein rapa, Zinc finger transcription factor TReP-132, TRERF1, BCAR2, RAPA, TREP132
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRERF1
Synonyms BCAR2, RAPA, TREP132
Function Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:11349124, ECO:0000269|PubMed:16371131}
Tissue Location Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells
Research Areas
Citations (0)
citation

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Background

TREF1 encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.

References

Gizard,F. Mol. Cell. Biol. 26 (20), 7632-7644 (2006)Gizard,F. Mol. Cell. Biol. 25 (11), 4335-4348 (2005)Beausoleil,S.A. Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)Gizard,F. J. Mol. Endocrinol. 32 (2), 557-569 (2004)

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$ 277.78
Cat# BP9356b
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