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IMP4 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96G21
Peptide ID 91109168
Additional Information
Other Names U3 small nucleolar ribonucleoprotein protein IMP4, U3 snoRNP protein IMP4, Brix domain-containing protein 4, IMP4, BXDC4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IMP4
Synonyms BXDC4
Function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
Cellular Location Nucleus, nucleolus EMBL; AY364245; AAQ76804.1; -; mRNA EMBL; AK289878; BAF82567.1; -; mRNA EMBL; AK292345; BAF85034.1; -; mRNA EMBL; AK312808; BAG35666.1; -; mRNA EMBL; AC132479; AAY24076.1; -; Genomic_DNA EMBL; BC010042; AAH10042.1; -; mRNA CCDS; CCDS2160.1; - RefSeq; NP_001307233.1; NM_001320304.1 RefSeq; NP_001307234.1; NM_001320305.1 RefSeq; NP_001307235.1; NM_001320306.1 RefSeq; NP_001307236.1; NM_001320307.1 RefSeq; NP_001307238.1; NM_001320309.1 RefSeq; NP_001307239.1; NM_001320310.1 RefSeq; NP_001307240.1; NM_001320311.1 RefSeq; NP_219484.1; NM_033416.2 UniGene; Hs.91579; - ProteinModelPortal; Q96G21; - SMR; Q96G21; - BioGrid; 124984; 35 CORUM; Q96G21; - IntAct; Q96G21; 3 MINT; Q96G21; - STRING; 9606.ENSP00000259239; - iPTMnet; Q96G21; - PhosphoSitePlus; Q96G21; - BioMuta; IMP4; - DMDM; 73621060; - EPD; Q96G21; - MaxQB; Q96G21; - PaxDb; Q96G21; - PeptideAtlas; Q96G21; - PRIDE; Q96G21; - ProteomicsDB; 76583; - DNASU; 92856; - Ensembl; ENST00000259239; ENSP00000259239; ENSG00000136718 GeneID; 92856; - KEGG; hsa:92856; - UCSC; uc002tra.2; human CTD; 92856; - EuPathDB; HostDB:ENSG00000136718.9; - GeneCards; IMP4; - HGNC; HGNC:30856; IMP4 HPA; HPA066222; - HPA; HPA066673; - MIM; 612981; gene neXtProt; NX_Q96G21; - OpenTargets; ENSG00000136718; - PharmGKB; PA142671656; - eggNOG; KOG2781; Eukaryota eggNOG; COG2136; LUCA GeneTree; ENSGT00550000074987; - HOGENOM; HOG000172063; - HOVERGEN; HBG056795; - InParanoid; Q96G21; - KO; K14561; - OMA; FFNISDV; - OrthoDB; EOG091G0GP1; - PhylomeDB; Q96G21; - TreeFam; TF300016; - Reactome; R-HSA-6790901; rRNA modification in the nucleus and cytosol Reactome; R-HSA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol ChiTaRS; IMP4; human GeneWiki; IMP4; - GenomeRNAi; 92856; - PRO; PR:Q96G21; - Proteomes; UP000005640; Chromosome 2 Bgee; ENSG00000136718; - CleanEx; HS_IMP4; - ExpressionAtlas; Q96G21; baseline and differential Genevisible; Q96G21; HS GO; GO:0001650; C:fibrillar center; IDA:HPA GO; GO:0034457; C:Mpp10 complex; IDA:MGI GO; GO:0005730; C:nucleolus; IDA:HGNC GO; GO:0005654; C:nucleoplasm; TAS:Reactome GO; GO:0030684; C:preribosome; IDA:MGI GO; GO:0032040; C:small-subunit processome; IBA:GO_Central GO; GO:0042134; F:rRNA primary transcript binding; IBA:GO_Central GO; GO:0030515; F:snoRNA binding; IBA:GO_Central GO; GO:0006364; P:rRNA processing; IBA:GO_Central InterPro; IPR007109; Brix Pfam; PF04427; Brix; 1 SMART; SM00879; Brix; 1 PROSITE; PS50833; BRIX; 1 1: Evidence at protein level; Complete proteome; Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; rRNA processing CHAIN 1 291 U3 small nucleolar ribonucleoprotein protein IMP4 /FTId=PRO_0000120236 DOMAIN 83 264 Brix. {ECO:0000255|PROSITE- ProRule:PRU00034} COMPBIAS 3 48 Arg-rich SEQUENCE 291 AA; 33757 MW; 460A05DFFE70C580 CRC64; MLRREARLRR EYLYRKAREE AQRSAQERKE RLRRALEENR LIPTELRREA LALQGSLEFD DAGGEGVTSH VDDEYRWAGV EDPKVMITTS RDPSSRLKMF AKELKLVFPG AQRMNRGRHE VGALVRACKA NGVTDLLVVH EHRGTPVGLI VSHLPFGPTA YFTLCNVVMR HDIPDLGTMS EAKPHLITHG FSSRLGKRVS DILRYLFPVP KDDSHRVITF ANQDDYISFR HHVYKKTDHR NVELTEVGPR FELKLYMIRL GTLEQEATAD VEWRWHPYTN TARKRVFLST E
Research Areas
Citations (0)

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Background

IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing.

References

Hillier,L.W. Nature 434 (7034), 724-731 (2005)Andersen,J.S.Nature 433 (7021), 77-83 (2005)Granneman,S.Nucleic Acids Res. 31 (7), 1877-1887 (2003)

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$ 80.00
Cat# BP9358b
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