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PLCB4 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15147
Peptide ID 80612101
Additional Information
Gene ID 5332
Other Names 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-4, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4, PLCB4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLCB4
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.
Tissue Location Preferentially expressed in the retina.
Research Areas
Citations (0)

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Background

PLCB4 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina.

References

Okada, Y., et al. Hum. Mol. Genet. (2010) In press Sjoholm, L.K., et al. J Circadian Rhythms 8 (1), 1 (2010) Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)

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$ 80.00
Cat# BP9375b
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