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LIPE Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q05469
Peptide ID 80612103
Additional Information
Gene ID 3991
Other Names Hormone-sensitive lipase, HSL, LIPE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIPE
Function In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
Cellular Location Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation
Research Areas
Citations (0)

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Background

LIPE has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.

References

Bezaire, V., et al. FEBS Lett. 583(18):3045-3049(2009)Chen, H.H., et al. Am. J. Clin. Nutr. 90(2):255-262(2009)Kuzmin, A., et al. Biol. Reprod. 81(2):319-326(2009)Bezaire, V., et al. J. Biol. Chem. 284(27):18282-18291(2009)Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)

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$ 80.00
Cat# BP9376b
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