|Other Names||Elongation factor 1-alpha 2, EF-1-alpha-2, Eukaryotic elongation factor 1 A-2, eEF1A-2, Statin-S1, EEF1A2, EEF1AL, STN|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.|
|Tissue Location||Brain, heart, and skeletal muscle.|
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EEF1A2 encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.
Yanaka, N., et al. Biosci. Biotechnol. Biochem. 73(12):2809-2811(2009)Lee, M.H., et al. Ann. N. Y. Acad. Sci. 1171, 87-93 (2009) :Cao, H., et al. Biochem. Biophys. Res. Commun. 380(1):11-16(2009)Soares, D.C., et al. PLoS ONE 4 (7), E6315 (2009) :Jeganathan, S., et al. Mol. Cell. Biol. 28(14):4549-4561(2008)
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