|Other Names||Ras-related protein Rab-18, RAB18|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
RAB18 proteins are members of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles.
Dejgaard, S.Y., et al. J. Cell. Sci. 121 (PT 16), 2768-2781 (2008) :Vazquez-Martinez, R., et al. J. Clin. Endocrinol. Metab. 93(6):2269-2276(2008)Ohsaki, Y., et al. Biochem. Biophys. Res. Commun. 347(1):279-287(2006)Martin, S., et al. J. Biol. Chem. 280(51):42325-42335(2005)Dou, T., et al. DNA Seq. 16(3):230-234(2005)
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