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FBXL5 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UKA1
Peptide ID 91009077
Additional Information
Gene ID 26234
Other Names F-box/LRR-repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, p45SKP2-like protein, FBXL5, FBL4, FBL5, FLR1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXL5
Synonyms FBL4, FBL5, FLR1
Function Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Cellular Location Cytoplasm, perinuclear region
Research Areas
Citations (0)

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Salahudeen, A.A., et al. Science 326(5953):722-726(2009)Vashisht, A.A., et al. Science 326(5953):718-721(2009)Zhang, N., et al. Biochem. Biophys. Res. Commun. 359(1):34-39(2007)Ilyin, G.P., et al. Genomics 67(1):40-47(2000)Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)

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$ 80.00
Cat# BP9409a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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