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ACP1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P24666 |
|---|
| Gene ID | 52 |
|---|---|
| Other Names | Low molecular weight phosphotyrosine protein phosphatase, LMW-PTP, LMW-PTPase, Adipocyte acid phosphatase, Low molecular weight cytosolic acid phosphatase, Red cell acid phosphatase 1, ACP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ACP1 (HGNC:122) |
|---|---|
| Function | Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2. |
| Cellular Location | Cytoplasm. |
| Tissue Location | [Isoform 2]: Expressed in T-lymphocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACP1 belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios.
References
Saccucci, P., et al. Med. Sci. Monit. 15 (10), CR511-CR517 (2009) :Shu, Y.H., et al. J. Clin. Endocrinol. Metab. 94(10):4094-4102(2009)Apelt, N., et al. Metab. Clin. Exp. 58(10):1415-1423(2009)Banci, M., et al. Cardiology 113(4):236-242(2009)Rousseff, R.T., et al. Neuropediatrics 39(6):354-356(2008)
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