|Other Names||Leucine-rich repeat-containing protein 17, p37NB, LRRC17, P37NB|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity).|
|Cellular Location||Secreted, extracellular space.|
|Tissue Location||Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells|
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Provided below are standard protocols that you may find useful for product applications.
LRC17 involved in bone homeostasis. This protein acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors
Kim, T., et al. J. Biol. Chem. 284(22):15308-15316(2009)Kim, D., et al. Biochim. Biophys. Acta 1309(3):183-188(1996)
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