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HSB11 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y547 |
|---|
| Gene ID | 51668 |
|---|---|
| Other Names | Intraflagellar transport protein 25 homolog, Heat shock protein beta-11, Hspb11, Placental protein 25, PP25, HSPB11, C1orf41, IFT25 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IFT25 (HGNC:25019) |
|---|---|
| Synonyms | C1orf41, HSPB11 |
| Function | Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity). |
| Cellular Location | Cell projection, cilium {ECO:0000250|UniProtKB:Q9D6H2} |
| Tissue Location | Detected in placenta.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Follit, J.A., et al. Cell Motil. Cytoskeleton 66(8):457-468(2009)Bellyei, S., et al. Eur. J. Cell Biol. 86(3):161-171(2007)Pozsgai, E., et al. BMC Cancer 7, 233 (2007) :Bohn, H., et al. Arch. Gynecol. Obstet. 248(3):111-115(1991)
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