|Other Names||Intraflagellar transport protein 25 homolog, Heat shock protein beta-11, Hspb11, Placental protein 25, PP25, HSPB11, C1orf41, IFT25|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly (By similarity).|
|Cellular Location||Cell projection, cilium.|
|Tissue Location||Detected in placenta.|
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Follit, J.A., et al. Cell Motil. Cytoskeleton 66(8):457-468(2009)Bellyei, S., et al. Eur. J. Cell Biol. 86(3):161-171(2007)Pozsgai, E., et al. BMC Cancer 7, 233 (2007) :Bohn, H., et al. Arch. Gynecol. Obstet. 248(3):111-115(1991)
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