|Other Names||Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, SERPINF2, AAP, PLI|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
SERPINF2 encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway.
# Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)# Cleary, D.B., et al. J. Thromb. Haemost. 7(11):1947-1949(2009)# Svenningsen, P., et al. J. Am. Soc. Nephrol. 20(2):299-310(2009)# Tseng, I.C., et al. Am. J. Physiol., Cell Physiol. 295 (2), C423-C431 (2008) # Lee, K.N., et al. Blood 103(10):3783-3788(2004)
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