|Other Names||Olfactomedin-like protein 3, HNOEL-iso, hOLF44, OLFML3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.|
|Tissue Location||Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.|
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Provided below are standard protocols that you may find useful for product applications.
Fautsch, M.P., et al. Exp. Eye Res. 82(6):1046-1052(2006)Zeng, L.C., et al. FEBS Lett. 571 (1-3), 74-80 (2004) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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