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MAFA Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NHW3
Additional Information
Gene ID 389692
Other Names Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:11416124, ECO:0000269|PubMed:12368292}. Note=Detected in nuclei of pancreas islet beta cells.
Research Areas
Citations (0)

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MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.


Kondo, T., et al. Mol. Endocrinol. 23(8):1281-1290(2009)Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009) Garin, I., et al. Diabet. Med. 26(7):746-748(2009)Vanderford, N.L., et al. Arch. Biochem. Biophys. 480(2):138-142(2008)Martin, C.C., et al. J. Mol. Endocrinol. 41(5):315-328(2008)

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$ 80.00
Cat# BP9440b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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