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AFM Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P43652 |
|---|
| Gene ID | 173 |
|---|---|
| Other Names | Afamin, Alpha-albumin, Alpha-Alb, AFM, ALB2, ALBA |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AFM |
|---|---|
| Synonyms | ALB2, ALBA |
| Function | Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720). Binds vitamin E (PubMed:15952736, PubMed:12463752). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed:15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed:19046407). |
| Cellular Location | Secreted |
| Tissue Location | High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
AFM is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.
References
Dieplinger, H., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1127-1133(2009)Kratzer, I., et al. J. Neurochem. 108(3):707-718(2009)Ramachandran, P., et al. J. Proteome Res. 5(6):1493-1503(2006)Hu, Y., et al. Mol. Cell Proteomics 4(12):2000-2009(2005)Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)Bunkenborg, J., et al. Proteomics 4(2):454-465(2004)
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