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CYB5R3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P00387
Peptide ID 80513097
Additional Information
Gene ID 1727
Other Names NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3 soluble form, CYB5R3, DIA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYB5R3
Synonyms DIA1
Function Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
Cellular Location Isoform 1: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Isoform 2 is expressed at late stages of erythroid maturation
Research Areas
Citations (0)

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CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain.


Sacco, J.C., et al. Pharmacogenet. Genomics 20(1):26-37(2010)Brajovich, M.L., et al. Immunol. Invest. 38(6):551-559(2009)Fermo, E., et al. Blood Cells Mol. Dis. 41(1):50-55(2008)Brandt, D.T., et al. J. Cell Biol. 178(2):193-200(2007)Fernandez-Borja, M., et al. J. Cell. Sci. 118 (PT 12), 2661-2670 (2005)

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$ 80.00
Cat# BP9448a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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