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RAMP2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O60895
Peptide ID 90805098
Additional Information
Gene ID 10266
Other Names Receptor activity-modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2, RAMP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAMP2
Function Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Strongly expressed in lung, breast, immune system and fetal tissues.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.


Kuwasako, K., et al. Biochem. Biophys. Res. Commun. 392(3):380-385(2010)Michou, L., et al. Clin. Exp. Rheumatol. 26(6):1083-1086(2008)Qi, T., et al. Mol. Pharmacol. 74(4):1059-1071(2008)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Kuwasako, K., et al. J. Biol. Chem. 275(38):29602-29609(2000)Aldecoa, A., et al. FEBS Lett. 471 (2-3), 156-160 (2000)

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$ 80.00
Cat# BP9462c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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