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IL26 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NPH9
Peptide ID 90805051
Additional Information
Gene ID 55801
Other Names Interleukin-26, IL-26, Protein AK155, IL26, AK155
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL26
Synonyms AK155
Function May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Cellular Location Secreted.
Tissue Location Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
Research Areas
Citations (0)

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Background

IL26 is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri.

References

??iezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)??ilverberg, M.S., et al. Nat. Genet. 41(2):216-220(2009)??antarci, O.H., et al. Arch. Neurol. 65(3):349-357(2008)??or, S., et al. J. Biol. Chem. 279(32):33343-33351(2004)

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$ 80.00
Cat# BP9472c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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