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C11orf30 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q7Z589 |
|---|
| Gene ID | 56946 |
|---|---|
| Other Names | Protein EMSY, EMSY, C11orf30 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EMSY (HGNC:18071) |
|---|---|
| Synonyms | C11orf30 |
| Function | Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin (PubMed:14651845). Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 (PubMed:14651845). Mediates ligand-dependent transcriptional activation by nuclear hormone receptors (PubMed:19131338). |
| Cellular Location | Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.
References
??sparza-Gordillo, J., et al. Nat. Genet. 41(5):596-601(2009)??arapaty, S., et al. J. Biol. Chem. 284(12):7542-7552(2009)??avaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)??ega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
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