|Other Names||T-cell differentiation antigen CD6, T12, TP120, CD6, CD6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in cell adhesion. Binds to CD166.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
CD6 is a monomeric 105- or 130-kD membrane glycoprotein that is involved in T-cell activation. The size difference between the 2 CD6 forms is due to differences in phosphorylation (Robinson et al., 1995 [PubMed 7589069]).
??avila, S., et al. Genes Immun. (2010) In press :??e Jager, P.L., et al. Lancet Neurol 8(12):1111-1119(2009)??ohnson, B.A., et al. Genes Immun. (2009) In press :??e Jager, P.L., et al. Nat. Genet. 41(7):776-782(2009)??lonso, R., et al. Hybridoma (Larchmt) 27(4):291-301(2008)
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