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ACAD8 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UKU7
Additional Information
Gene ID 27034
Other Names Isobutyryl-CoA dehydrogenase, mitochondrial, 1399-, Activator-recruited cofactor 42 kDa component, ARC42, Acyl-CoA dehydrogenase family member 8, ACAD-8, ACAD8, ARC42, IBD
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACAD8 (HGNC:87)
Synonyms ARC42, IBD
Function Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway (PubMed:11013134, PubMed:12359132, PubMed:16857760). To a lesser extent, also able to catalyze the oxidation of (2S)-2- methylbutanoyl-CoA (PubMed:11013134, PubMed:12359132).
Cellular Location Mitochondrion
Tissue Location Detected at comparable levels in heart, lung, brain, skeletal muscle, pancreas and placenta. Weakly expressed in liver and kidney.
Research Areas
Citations (0)
citation

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Background

ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. This protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine.

References

Wollmer, M.A., et al. Neurogenetics 8(3):179-188(2007)Ma, J., et al. Atherosclerosis 191(1):63-72(2007)Battaile, K.P., et al. J. Biol. Chem. 279(16):16526-16534(2004)

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$ 277.78
Cat# BP9488c
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