|Other Names||Transcription factor GATA-5, GATA-binding factor 5, GATA5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor required during cardiovascular development (PubMed:23289003). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (By similarity). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (PubMed:25543888).|
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Provided below are standard protocols that you may find useful for product applications.
GATA5 is a transcription factor that contains two GATA-type zinc fingers. This protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Hellebrekers, D.M., et al. Clin. Cancer Res. 15(12):3990-3997(2009)Fu, B., et al. Cancer Biol. Ther. 6(10):1546-1552(2007)Guo, M., et al. Int. J. Cancer 119(9):2078-2083(2006)Wakana, K., et al. Cancer Lett. 241(2):281-288(2006)
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