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GBE1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q04446 |
|---|
| Gene ID | 2632 |
|---|---|
| Other Names | 4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme, GBE1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GBE1 |
|---|---|
| Function | Required for normal glycogen accumulation (PubMed:8463281, PubMed:26199317, PubMed:8613547). The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule (Probable). |
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Provided below are standard protocols that you may find useful for product applications.
Background
GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
References
Konstantinidou, A.E., et al. Placenta 29(4):378-381(2008)Massa, R., et al. Muscle Nerve 37(4):530-536(2008)Bruno, C., et al. Acta Myol 26(1):75-78(2007)
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