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WAC Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BTA9
Peptide ID 91102004
Additional Information
Gene ID 51322
Other Names WW domain-containing adapter protein with coiled-coil, WAC, KIAA1844
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WAC
Synonyms KIAA1844
Function Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.
Cellular Location Nucleus speckle. Nucleus. Note=In distinct nuclear speckles Colocalizes with pre-mRNA processing complexes (By similarity)
Research Areas
Citations (0)

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WAC contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known.


Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)Lim, J., et al. Cell 125(4):801-814(2006)Deloukas, P., et al. Nature 429(6990):375-381(2004)

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$ 80.00
Cat# BP9537c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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