|Other Names||Replication initiator 1, 60 kDa origin-specific DNA-binding protein, 60 kDa replication initiation region protein, ATT-binding protein, DHFR oribeta-binding protein RIP60, Zinc finger protein 464, REPIN1, RIP60, ZNF464|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending.|
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Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. REPIN1 binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. It facilitates DNA bending.
??im, M.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 103(35):13074-13079(2006)??ontigny, W.J., et al. Nucleic Acids Res. 29(9):1982-1988(2001)??ouchens, C.R., et al. Nucleic Acids Res. 28(2):570-581(2000)??astrangelo, I.A., et al. J. Mol. Biol. 232(3):766-778(1993)??addle, M.S., et al. Mol. Cell. Biol. 10(12):6236-6243(1990)??ailey, L., et al. Mol. Cell. Biol. 10(12):6225-6235(1990)
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