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REPIN1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BWE0 |
|---|
| Gene ID | 29803 |
|---|---|
| Other Names | Replication initiator 1, 60 kDa origin-specific DNA-binding protein, 60 kDa replication initiation region protein, ATT-binding protein, DHFR oribeta-binding protein RIP60, Zinc finger protein 464, REPIN1, RIP60, ZNF464 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | REPIN1 |
|---|---|
| Synonyms | RIP60, ZNF464 |
| Function | Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'- ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. Facilitates DNA bending. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. REPIN1 binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. It facilitates DNA bending.
References
??im, M.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 103(35):13074-13079(2006)??ontigny, W.J., et al. Nucleic Acids Res. 29(9):1982-1988(2001)??ouchens, C.R., et al. Nucleic Acids Res. 28(2):570-581(2000)??astrangelo, I.A., et al. J. Mol. Biol. 232(3):766-778(1993)??addle, M.S., et al. Mol. Cell. Biol. 10(12):6236-6243(1990)??ailey, L., et al. Mol. Cell. Biol. 10(12):6225-6235(1990)
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