|Other Names||Retinol dehydrogenase 14, 111-, Alcohol dehydrogenase PAN2, RDH14, PAN2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.|
|Tissue Location||Expressed in brain, kidney, pancreas and placenta|
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RDH14 exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. It displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.
??ersson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :??an Es, M.A., et al. Nat. Genet. 40(1):29-31(2008)??chymick, J.C., et al. Lancet Neurol 6(4):322-328(2007)??lark, H.F., et al. Genome Res. 13(10):2265-2270(2003)??omarev, S.I., et al. Invest. Ophthalmol. Vis. Sci. 44(6):2588-2596(2003)
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