|Other Names||HAUS augmin-like complex subunit 6, HAUS6, DGT6, FAM29A, KIAA1574|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||DGT6, FAM29A, KIAA1574|
|Function||Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin.|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules|
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Provided below are standard protocols that you may find useful for product applications.
HAUS6 is required for progression through mitosis. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin.
??awo, S., et al. Curr. Biol. 19(10):816-826(2009)??ehara, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106(17):6998-7003(2009)??hu, H., et al. J. Cell Biol. 183(5):835-848(2008)??oshima, G., et al. J. Cell Biol. 181(3):421-429(2008)??ugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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