|Other Names||Exocyst complex component 1, Exocyst complex component Sec3, EXOC1, SEC3, SEC3L1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|
|Cellular Location||Midbody, Midbody ring. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with CNTRL/centriolin at the midbody ring|
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Provided below are standard protocols that you may find useful for product applications.
EXOC1 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
??ndersen, N.J., et al. Mol. Biol. Cell 21(1):152-164(2010)??akurai-Yageta, M., et al. J. Cell Biol. 181(6):985-998(2008)??su, S.C., et al. Int. Rev. Cytol. 233, 243-265 (2004) :??oskalenko, S., et al. J. Biol. Chem. 278(51):51743-51748(2003)??noue, M., et al. Nature 422(6932):629-633(2003)
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