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EXOC1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NV70
Additional Information
Gene ID 55763
Other Names Exocyst complex component 1, Exocyst complex component Sec3, EXOC1, SEC3, SEC3L1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EXOC1
Synonyms SEC3, SEC3L1
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Cellular Location Midbody, Midbody ring. Cytoplasm. Cytoplasm, perinuclear region. Cell membrane. Note=Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). Localizes in cell membrane in the presence of SLC6A9 (PubMed:16181645).
Research Areas
Citations (0)
citation

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Background

EXOC1 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.

References

??ndersen, N.J., et al. Mol. Biol. Cell 21(1):152-164(2010)??akurai-Yageta, M., et al. J. Cell Biol. 181(6):985-998(2008)??su, S.C., et al. Int. Rev. Cytol. 233, 243-265 (2004) :??oskalenko, S., et al. J. Biol. Chem. 278(51):51743-51748(2003)??noue, M., et al. Nature 422(6932):629-633(2003)

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$ 277.78
Cat# BP9562b
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