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MORG1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BRX9
Peptide ID 90904150
Additional Information
Gene ID 84292
Other Names WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83, MORG1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR83
Synonyms MORG1
Function Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear
Research Areas
Citations (0)

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MORG1 is a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome.


??aase, D., et al. Neurosci. Lett. 455(1):46-50(2009)??opfer, U., et al. J. Biol. Chem. 281(13):8645-8655(2006)??omastek, T., et al. Proc. Natl. Acad. Sci. U.S.A. 101(18):6981-6986(2004)

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$ 80.00
Cat# BP9575c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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