|Other Names||Aquaporin-10, AQP-10, Aquaglyceroporin-10, Small intestine aquaporin, AQP10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum|
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Provided below are standard protocols that you may find useful for product applications.
AQP10 is a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea.
??hapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)??uke, M.M., et al. Stroke 40(2):363-368(2009)??ohly, H.H., et al. Int J Environ Res Public Health 5(2):115-119(2008)??hiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)??lach, C.F., et al. FEBS Lett. 581(17):3183-3188(2007)
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