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SGSH Antibody (C-Term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P51688
Other Accession NP_000190
Additional Information
Gene ID 6448
Other Names N-sulphoglucosamine sulphohydrolase, Sulfoglucosamine sulfamidase, Sulphamidase, SGSH, HSS
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SGSH
Synonyms HSS
Function Catalyzes a step in lysosomal heparan sulfate degradation.
Cellular Location Lysosome.
Research Areas
Citations (0)
citation

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Background

SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

References

??leat, D.E., et al. Mol. Cell Proteomics 5(4):686-701(2006)??ekri, S., et al. J. Inherit. Metab. Dis. 28(4):601-602(2005)??uschol, N., et al. Hum. Mutat. 23(6):559-566(2004)??hang, H., et al. Nat. Biotechnol. 21(6):660-666(2003)

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$ 277.78
Cat# BP9579b
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