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TIFA Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96CG3
Peptide ID 91109309
Additional Information
Gene ID 92610
Other Names TRAF-interacting protein with FHA domain-containing protein A, Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, TRAF2-binding protein, TIFA, T2BP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIFA
Synonyms T2BP
Function Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
Research Areas
Citations (0)

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Background

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

References

??inoda, Y., et al. Biochem. Biophys. Res. Commun. 344(3):1023-1030(2006)??a, C.K., et al. Proc. Natl. Acad. Sci. U.S.A. 101(43):15318-15323(2004)??atsuda, A., et al. Oncogene 22(21):3307-3318(2003)??akatsuna, H., et al. J. Biol. Chem. 278(14):12144-12150(2003)

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$ 80.00
Cat# BP9587a
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