|Other Names||Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase, CHAT|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.|
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CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease.
Shaffer, J.R., et al. Nutr Metab Cardiovasc Dis (2010) In pressBeck, M., et al. Cell Tissue Res. 338(1):37-51(2009)Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
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