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MICAL2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O94851
Peptide ID 80902025
Additional Information
Gene ID 9645
Other Names Protein-methionine sulfoxide oxidase MICAL2, 11413-, Molecule interacting with CasL protein 2, MICAL-2, MICAL2, KIAA0750, MICAL2PV1, MICAL2PV2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0750, MICAL2PV1, MICAL2PV2
Function Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine- sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Ashida, S., et al. Clin. Cancer Res. 12(9):2767-2773(2006)Fischer, J., et al. Biochem. Biophys. Res. Commun. 328(2):415-423(2005)

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$ 80.00
Cat# BP9597a
(40 western blots)
Availability: In Stock
Bulk Size
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