|Other Names||Golgi to ER traffic protein 4 homolog, Conserved edge-expressed protein, Transmembrane domain recognition complex 35 kDa subunit, TRC35, GET4, C7orf20, CEE, TRC35|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C7orf20, CEE, TRC35|
|Function||Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.|
|Cellular Location||Cytoplasm, cytosol|
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Provided below are standard protocols that you may find useful for product applications.
CEE (Conserved edge expressed protein) belongs to the UPF0363 family.
Chang, Y.W., et al. J. Biol. Chem. 285(13):9962-9970(2010)Fernandes, J.M., et al. Genomics 91(4):315-325(2008)
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