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CLN6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NWW5 |
|---|
| Gene ID | 54982 |
|---|---|
| Other Names | Ceroid-lipofuscinosis neuronal protein 6, Protein CLN6, CLN6 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CLN6 |
|---|---|
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
References
Al-Muhaizea, M.A., et al. Pediatr. Neurol. 41(1):74-76(2009)Oresic, K., et al. Biosci. Rep. 29(3):173-181(2009)
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