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CENPI Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92674
Additional Information
Gene ID 2491
Other Names Centromere protein I, CENP-I, FSH primary response protein 1, Follicle-stimulating hormone primary response protein, Interphase centromere complex protein 19, Leucine-rich primary response protein 1, CENPI, FSHPRH1, ICEN19, LRPR1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CENPI
Synonyms FSHPRH1, ICEN19, LRPR1
Function Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle- stimulating hormone.
Cellular Location Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
Research Areas
Citations (0)
citation

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Background

CENPI is involved in the response of gonadal tissues to follicle-stimulating hormone.

References

Cheeseman, I.M., et al. Mol. Biol. Cell 19(2):587-594(2008)Izuta, H., et al. Genes Cells 11(6):673-684(2006)Okada, M., et al. Nat. Cell Biol. 8(5):446-457(2006)

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$ 277.78
Cat# BP9618c
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