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HSPB6 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O14558
Peptide ID 91013145
Additional Information
Gene ID 126393
Other Names Heat shock protein beta-6, HspB6, Heat shock 20 kDa-like protein p20, HSPB6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSPB6
Function Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Translocates to nuclear foci during heat shock.
Research Areas
Citations (0)

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Background

HSPB6 is associated with actin (see MIM 102540) and modulates smooth muscle relaxation (Tessier et al., 2003 [PubMed 12842460]).

References

Fuchs, M., et al. Biochem. J. 425(1):245-255(2010)Qian, J., et al. Circ. Res. 105(12):1223-1231(2009)Bagneris, C., et al. J. Mol. Biol. 392(5):1242-1252(2009)

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$ 80.00
Cat# BP9629c
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