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ERF3B Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IYD1
Peptide ID 91109043
Additional Information
Gene ID 23708
Other Names Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, Eukaryotic peptide chain release factor subunit 3b, eRF3b, G1 to S phase transition protein 2 homolog, GSPT2, ERF3B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSPT2
Synonyms ERF3B
Function Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in IUCC stage II colorectal cancer (CRC).
Research Areas
Citations (0)

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ERF3B encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.


Cheng, Z., et al. Genes Dev. 23(9):1106-1118(2009)Zhouravleva, G., et al. IUBMB Life 58(4):199-202(2006)Chauvin, C., et al. Mol. Cell. Biol. 25(14):5801-5811(2005)Hoshino, S., et al. J. Biol. Chem. 274(24):16677-16680(1999)Hansen, L.L., et al. Cytogenet. Cell Genet. 86 (3-4), 250-251 (1999)

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$ 80.00
Cat# BP9663c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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