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CYTH3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43739
Peptide ID 90921072
Additional Information
Gene ID 9265
Other Names Cytohesin-3, ARF nucleotide-binding site opener 3, Protein ARNO3, General receptor of phosphoinositides 1, Grp1, PH, SEC7 and coiled-coil domain-containing protein 3, CYTH3, ARNO3, GRP1, PSCD3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYTH3
Synonyms ARNO3, GRP1, PSCD3
Function Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP.
Cellular Location Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate
Tissue Location Almost absent from liver, thymus and peripheral blood lymphocytes
Research Areas
Citations (0)

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This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.


Morishige, M., et al. Nat. Cell Biol. 10(1):85-92(2008) Poirier, M.B., et al. Mol. Endocrinol. 19(8):1991-2005(2005) Nevrivy, D.J., et al. J. Biol. Chem. 275(22):16827-16836(2000) Ogasawara, M., et al. J. Biol. Chem. 275(5):3221-3230(2000)

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$ 80.00
Cat# BP9673b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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