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CES3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6UWW8
Peptide ID 90904062
Additional Information
Gene ID 23491
Other Names Carboxylesterase 3, Liver carboxylesterase 31 homolog, CES3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CES3
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Cellular Location Endoplasmic reticulum lumen.
Tissue Location Expressed in liver, colon and small intestine.
Research Areas
Citations (0)

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Carboxylesterase 3 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.


Sanghani, S.P., et al. Protein Pept. Lett. 16(10):1207-1214(2009) Fukami, T., et al. Pharmacogenet. Genomics 18(10):911-920(2008) Sanghani, S.P., et al. Drug Metab. Dispos. 32(5):505-511(2004) Sanghani, S.P., et al. Clin. Cancer Res. 9(13):4983-4991(2003)

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$ 80.00
Cat# BP9674b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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