|Other Names||Butyrophilin subfamily 3 member A2, BTN3A2, BT32, BTF3, BTF4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||BT3.2, BTF3, BTF4|
|Function||Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Detected in T-cells and natural killer cells.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the immunoglobulin superfamily, containing two Ig domains with similarity to Ig variable and Ig constant domains. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus on chromosome 6 in the seven member BTN cluster, which includes butyrophilin, and three members each of the BTN2 and BTN3 subfamilies.
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009) Shi, J., et al. Nature 460(7256):753-757(2009) Viken, M.K., et al. Genes Immun. 10(4):323-333(2009) Mungall, A.J., et al. Nature 425(6960):805-811(2003) Rhodes, D.A., et al. Genomics 71(3):351-362(2001)
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