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BT3A2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P78410 |
|---|
| Gene ID | 11118 |
|---|---|
| Other Names | Butyrophilin subfamily 3 member A2, BTN3A2, BT32, BTF3, BTF4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BTN3A2 |
|---|---|
| Synonyms | BT3.2, BTF3, BTF4 |
| Function | Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Detected in T-cells and natural killer cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the immunoglobulin superfamily, containing two Ig domains with similarity to Ig variable and Ig constant domains. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus on chromosome 6 in the seven member BTN cluster, which includes butyrophilin, and three members each of the BTN2 and BTN3 subfamilies.
References
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009) Shi, J., et al. Nature 460(7256):753-757(2009) Viken, M.K., et al. Genes Immun. 10(4):323-333(2009) Mungall, A.J., et al. Nature 425(6960):805-811(2003) Rhodes, D.A., et al. Genomics 71(3):351-362(2001)
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